The environments we inhabit and in which we interact as human beings are defined by the interweaving of physical and immaterial spaces - liquid and fluid - and historical, social and technological time, which outline their characteristics and morphologies. With digital technologies, it is possible to make a bidirectional and constant transition from the physical scale, which represents the container, to the digital scale, which constitutes the content. Multisensoriality, defined by the link between perception and the emotions that derive from it, becomes a fundamental element for the understanding of the human being and a fertile ground for innovative planning. The H2H approach brings human kind back to the center of the design of new relationships that, through design, allow the most profitable communication between the actors involved, reaching innovative solutions, both technological and meaningful. The EDME laboratory, within the Politecnico di Milano, is the result of a path of multidisciplinary integration (transdisciplinary) that synthesizes, in a systemic perspective, multi-scalar relationships that delineate the complex identity of a tool for investigation, interpretation and representation of experiential scenarios, experimentation and research. EDME integrates, in a physical space, innovative ICT technology and materials of the latest generation, to simulate complex activities and interactions. Didactics goes hand in hand with research: the Final Synthesis Workshop "Design of the New Relations" concludes the Master's degree course in Integrated Product Design at the Design Department of Politecnico di Milano. The aim of the course is to integrate tools, methods and knowledge acquired during the training path, in order to manage the design complexity related to the product-system, with a strong focus on innovative issues from a social, environmental, cultural and technological point of view. The Laboratory is divided into different phases that simulate the development of a professional project in collaboration with the companies involved: team building, analysis, development of a scenario, development of a concept. An interdisciplinary way to make innovation, with a mix of skills and approaches that creates synergies with high design potential.